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Because the sample sizes of published observational studies that investigated the association between SLE and smoking are generally small, statistical aggregation of data with the use of metaanalysis is one of the reasonable methodological approaches to increase the statistical power for examining the relationship

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How these patterns evolve may depend on the regulatory environment around e-cigarettes, as well as ongoing trends in the production and sale of marijuana-based products

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On the contrary, it may turn out to be the real case