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Science 367, 1434

Important limitation: Neither is FDA-approved, and human clinical data remains highly preliminary

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Wu X., Ma C., Han L., Nawaz M., Gao F., Zhang X., Yu P., Zhao C., Li L., Zhou A., Wang J., Moore J

This makes it a valuable option for patients with metabolic conditions such as diabetes or those who have not responded to hormone therapy alone

Croci I, Byrne NM, Choquette S, Hills AP, Chachay VS, Clouston AD, OMoore-Sullivan TM, Macdonald GA, Prins JB, Hickman IJ (2013) Whole-body substrate metabolism is associated with disease severity in patients with non-alcoholic fatty liver disease