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One of the main pathological signs of PD is the selective death of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and subsequent deregulation of the basal ganglia, resulting in aberrant motor control 2,3

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Group D, 4 weeks sections presented distortions in parenchymal tissue architecture with hemorrhagic exudations, degenerative fatty changes and inflammatory and necrotic cells with vacuolations (Fig

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Impaired Tissue Integrity Rationale: Frequent or severe nosebleeds can damage the nasal mucosa and surrounding tissues