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Despite these disease-specific patterns, the repeated involvement of TGF-/Smad, Wnt/-catenin, PI3K/AKT/mTOR, p38 MAPK, JAK/STAT, and NF-B suggests that senescence may represent a common therapeutic node across chronic lung diseases

Siegmund from the USC Norris Comprehensive Cancer Center and the Department of Population and Public Health Sciences, Keck School of Medicine of USC, University of Southern California

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One can be found in each of Vault 75, Vault 111 and Vault 114.