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22nd Century says it used a patent-protected process to control nicotine biosynthesis in the tobacco plant, enabling it to create a pack of cigarettes with about as much nicotine as one Marlboro

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This equates to more than 108,000 people quitting, not relapsing or not starting to smoke during that period, the WHO pointed out

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They found that none of these trials reported increases in the number of average cigarettes smoked per day among people assigned to the very low nicotine cigarettes