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Physical examination revealed a subcutaneous bulge of about 4cm in diameter in the left pretibial region with yellowish-purpuric overlying skin and a strikingly gummy consistency

These cells were derived from primary human alveolar epithelial cells (AECs) isolated from resected lung tissue and subsequently immortalized using InscreeneXs CI-Screen technology, as described by Lipps et al

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Decades of research show that smoking and smokeless tobacco products are harmful to dental health

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This assumption is based on the papers discussed above (Are e-cigarettes a gateway to smoking?)