They found e-cigarette aerosol exposure for 2 weeks produced a significant increase in oxidative stress and moderate macrophage-mediated inflammation, and significantly impaired pulmonary bacterial clearance, compared with air-exposed mice, following an intranasal infection with Streptococcus pneumonia
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As one review stated, "Nicotine is the addictive chemical in tobacco smoke, but its involvement in smoking-related harm (outside pregnancy) is very small, if any, compared to cigarette smoking." Another systematic review pointed out that nicotine can have a variety of potential health effects, from raising one's cardiovascular risk to causing birth defects in pregnant women
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Blood Clot Formation (First 24 Hours): After the extraction, a blood clot forms at the site, protecting the bone and nerves while promoting healing