These businesses piggybacked on the burgeoning compounded GLP-1RA market after Eli Lilly's tirzepatide, sold under the brand names Zepbound and Mounjaro for weight loss and type 2 diabetes respectively, was declared in short supply in 2022
The combined receptor engagement produces greater reductions in caloric intake and improved insulin sensitivity compared to GLP-1 agonism alone [2]
Thats about what wed expect
I also liked that GobyMeds asked more than just surface-level questions
Additionally, both drugs are associated with possible serious side effects, such as kidney failure, inflammation of the pancreas, and vision problems
PI3K activation leads to the phosphorylation of phosphatidylinositol-4,5-bisphosphate (PIP2), generating phosphatidylinositol-3,4,5-trisphosphate (PIP3) [31]