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Use a 4 mg dose if: You smoke more than 25 cigarettes a day (or an equivalent amount of nicotine)

Genetic differences influence which individuals will develop a nicotine addiction upon initial use of the drug

Preventing high risk behaviors, that include cigarette, cigar or pipe smoking, use of smokeless tobacco, and excessive use of alcohol are critical in preventing oral cancers

1 Despite the fact that most adult smokers want to quit, fewer than one in ten smokers succeed in quitting smoking each year

Comment: Its quite a serious drug to take and is only available on prescription

Supplementary Figure 10 Differentially abundant bacterial genera in dental sites of healthy and OSCC samples