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By stimulating catecholamine release (particularly norepinephrine), nicotine encourages the breakdown of stored fat (lipolysis) and shifts the body toward using fatty acids as an energy source

Cotinine can be a marker to detect exposure to nicotine as it has high sensitivity and its half-life is longer than other nicotine metabolites

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Quitting while pregnant greatly lowers how smoking affects fetal growth, but quitting early on is capable of fully eradicating the negative effects