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Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2016 Page last updated: February 4, 2026

The incidence of events in the composite endpoint was higher for each of the active treatments compared to placebo: Risk Differences (RDs) (95%CI) vs placebo were 2.7% (-0.05, 5.4) for CHANTIX, 2.2% (- 0.5, 4.9) for bupropion, and 0.4% (-2.2, 3.0) for NRT transdermal nicotine

If you feel nauseated at any point, slow down or take a 1520 minute break before continuing

DATA AVAILABILITY The data supporting this research are available from the authors on reasonable request

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Theres a wallet card on the bottom of this Users Guide