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Protrusions of M1-type microglia become larger in diameter and present an amoebic state, which have neuroinflammatory effects, while M2-type microglia have significantly more branching and longitudinally extended protrusions, executing an anti-inflammatory effect and having a neuroprotective function

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The combination of these two health conditions is called "overlap syndrome"

Tobacco smoke is a complex cocktail of at least 4,000 chemicals including at least 70 known carcinogens