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While nicotine may trigger faster bowel movements in the short term, long-term use can contribute to digestive issues like acid reflux, heartburn, stomach ulcers, IBS symptoms, constipation, or diarrhea

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Belgium, Colombia, Finland, Singapore, South Africa, Sri Lanka and Sweden are formally considering plain packaging

In addition, an intermediate power setting was chosen compared to our prior work, one that was purported to represent normal vaping conditions 4

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Chem Res Toxicol 15:677685 Prokopczyk B, Trushin N, Leszczynska J, Waggoner SE, El Bayoumy K (2001) Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways