While excessive training without adequate recovery can increase oxidative stress, regular movement appears to support greater resilience over time
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Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystineglutamate antiporter xCT
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Margis R, Dunand C, Teixeira FK, Margis-Pinheiro M
In this study, we aimed to investigate whether three drugs (sertraline, fluoxetine, and citalopram) from the selective serotonin reuptake inhibitor (SSRI) family, commonly used as antidepressants, could be repurposed as inhibitors of MRP1 and MRP7 transporters and reverse MDR in cancer cells