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Lydia Alexander, these DIY alternatives pose significant health risks as they are unregulated and potentially dangerous

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While the ATTAIN-1 trial successfully met its predetermined weight loss endpoints versus placebo, the weight loss percentage realized in the highest dose fell modestly short of investor expectations, with average weight loss of 12.4% versus placebo at 0.9%

A separate 2025 systematic review and meta-analysis published in the Journal of Thrombosis and Haemostasis analyzed 27 clinical trials involving more than 84,000 patients