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So [00:50:58] Jessica Wynn: internal medicine specialists, they'll tell you that you're only overwhelming your liver more, which is already working over time, and it turns into a vicious cycle that there's actually a name for, it's called alcoholism

Jama 298 , 26542664 (2007)

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Of course it didn't always have to be cigarette smoke

3 Impact of tobacco smoke on enzymatic drug metabolism Tobacco smoke is a complex mixture of polycyclic aromatic hydrocarbons (PAHs), ammonia, aromatic amines, phenols, carbonyls, hydrocyanic acid, and N-nitrosamines (Hoffmann and Hoffmann, 1997)