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Updated May 2026: The IQOS range has changed since this article was first published

However, people with certain underlying medical conditions may experience more frequent and severe cases of sinusitis

Shadel, Joan S

Treatment with both adenosine transporter inhibitor and A2AAR/A2BAR antagonists completely abolished adenosine's effect on barrier function, suggesting both are required for adenosine to exert a maximum effect on barrier function