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By adolescence, pregnant women who smoke tobacco are probably going to experience long-term declines in their regions cerebral gray matter [95] and white-matter integrity by adolescence [96]

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NNK treatment significantly increases macrophage infiltration and expression of pro-inflammatory mediators such as macrophage inflammatory protein 1 alpha (MIP-1, interleukin 1 beta (IL-1), and TGF- in mice neoplastic lesions (117)

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