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EBioMedicine 85 , 104304 (2022)

Clinical Application of GLP-1/GIP Dual Receptor Agonist (Tirzepatide) Currently, tirzepatide serves as a prototypical agent among the dual-receptor agonists of GLP-1 and GIP

The efficacy of systemic GLP-1R agonists to attenuate cocaine seeking is associated with decreased activity of dopamine cells in the VTA VTA dopamine neurons mediate the rewarding effects of cocaine and increased dopamine cell firing in the VTA is necessary for cocaine seeking 58,59

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3.2 Overview of Catharanthus roseus (L.) The Indian subcontinent is home to a diverse range of medicinal plants, many of which have not been researched to their full potential