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Finally, QIIME software (version 1.9.1) was employed for the evaluation of diversity and the generation of species abundance tables across various classification levels (Caporaso et al

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"Cigarette smoking or tobacco use is the leading cause of preventable death in Indiana, and we know that it is responsible for 34 percent of all cancer mortalities in the state," said Allie Kast Gregg of the American Cancer Society

(6) End-stage liver disease is accompanied by many debilitating symptoms: (9) Extreme fatigue Severe itching of the skin (pruritus) Abdominal swelling Hemorrhaging and enlargement of the veins, which can cause gastrointestinal bleeding Cognitive decline from the accumulation of toxins in the bloodstream, which can result in mild cognitive impairments (problems with thought processes), severe loss of brain functions, and coma

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Sociodemographic variables comprised age, sex, educational attainment and deprivation quintiles