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Findings In this observational cohort study of 8770 participants, former heavy smokers' risk of cardiovascular disease was significantly lower within 5 years of smoking cessation relative to current smokers (hazard ratio, 0.61) but remained significantly elevated for at least 5 to 10 years and possibly for 25 years after cessation relative to never smokers

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Cadmium exposure and cardiovascular disease in the 2005 Korea National Health and Nutrition Examination Survey

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"In this case, the applicant did not provide sufficient scientific evidence to demonstrate that the potential benefits for adult smokers outweigh the risks for youth