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Am J Transplant (2012) 12(3):6109.10.1111/j.1600-6143.2011.03820.x 13 BeutelspacherSCPillaiRWatsonMPTanPHTsangJMcClureMOet alFunction of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression

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Furthermore, smoking can cause jawbone deterioration, decreased vascular function, and lower oxygen levels in the blood all of which contribute to a higher chance of needing root canal therapy

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