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In addition, Western blot analysis showed that, compared with the CSE treatment group, the group with knockdown of miR-125a-5p had elevated Sp1 and SIRT1 expression, decreased HIF-1 acetylation levels, and decreased cell senescence markers p21 and p27 (Fig

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But for people who are thinking about the best way to stop smoking and are concerned about weight gain, I think what we are suggesting is that e-cigarettes should certainly be considered. Paul Aveyard, professor of behavioural medicine at the University of Oxford, said it was almost certain that nicotine-containing e-cigarettes would reduce weight gain among smokers attempting to quit

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