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In rats given BPC-157, serotonin levels in the brain increase in specific regions while simultaneously decreasing in other regions, such as the hippocampus.[ref] A 2020 study found that BPC-157 reduced leaky gut syndrome by stabilizing gut permeability after NSAID use.[ref] Reducing leaky gut theoretically can affect the gut-brain axis and reduce inflammation

This can help reduce the stigma around weight management

BPC 157 is known to expedite recovery by modulating the healing response, while TB 500 assists in tissue repair and flexibility enhancement

The 2013 paper by McCoy et al

The most common side effects are injection site reactions mild pain, redness, or swelling at the intramuscular injection site (typically deltoid or gluteal muscle)

A systematic review and meta-analysis of randomized controlled trials