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During this titration phase, appetite suppression gradually intensifiesweek one may bring subtle appetite reduction, while week three or four produces pronounced satiety

The authors emphasised that the findings showed association rather than causation

This review aims to summarize the evidence regarding the nephroprotective effects of glucagon-like peptide-1 receptor agonists (GLP-1RA) and tirzepatide and the putative mechanisms underlying the favorable renal profile of tirzepatide

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GLP-1s also affect the hypothalamus in the brain, which further reduces hunger even when losing weight