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Public Health Service, Washington, DC Djordjevic MV, Gay SL, Bush LP, Chaplin JF (1989) Tobacco-specific nitrosamine accumulation and distribution in flue-cured tobacco alkaloid isolines

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However, as IVW can be sensitive to heterogeneity and horizontal pleiotropy, we performed additional sensitivity analyses using complementary MR methods, including MR-Egger regression, the weighted median method, and the weighted mode estimator, to evaluate the robustness of our findings and to account for potential violations of the MR assumptions

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JACC Case Rep