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This staining effect is not just cosmetic

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However, this multiplicative effect cannot be estimated in our time series model because the time series analysis does not allow for interaction estimation

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Illicit market concerns: Higher prices have unfortunately contributed to growth in illicit tobacco trade (7), with HMRC estimates suggesting illicit cigarettes account for approximately 12% of total consumption, representing significant lost tax revenue

In the respiratory tract, smoking exacerbates inflammation, leading to increased mucus production, impaired ciliary function, and airway remodeling, which worsen the pathophysiology of respiratory diseases [15, 16]