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This is likely because the brain quickly adapts to the elevated dopamine levels which results in the users chasing the same effects with higher doses

doi: 10.1038/s41591-020-1051-9 40 DeshpandeD.MorganW

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Carbon monoxide reduces the ability to transport oxygen to the eyes, weakening ocular tissues, while nicotine constricts the eyes blood vessels, increasing the risk of developing serious vision problems Dr