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Exposure to high levels of ozone can be harmful to people and pets, so the machine should only be used in empty spaces, and the area should be well-ventilated afterward

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Trends in Cardiovascular Medicine, 26 (6), 515-523

Renfro, leaving Fort Worth at midnight, spent all night driving around East Texas

Although these unknown factors do not have pharmacological effects similar to nicotine and are probably not addictive, they definitely play a role in smoking behaviour