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Researchers at the Wellcome Trust Sanger Institute in the UK and Los Alamos National Laboratory in the US measured the catastrophic genetic damage caused by smoking in different organs of the body and identified several different mechanisms by which tobacco smoking causes mutations in DNA

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To this end, we utilized human monocyte THP1 cells and primary human peripheral blood macrophages, and C57BL/6 mice to assess the in vivo effects of cigarette smoke

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