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cytotoxic, mutagenic and proinflammatory substances contained in cigarettes Surfactant smoking is associated with reduced surfactant phospholipids fibrotic factors T helper type 1 (Th1) cells are a lineage of CD4 + effector T cell that promotes cell-mediated immune responses and is required for host defense against intracellular viral and bacterial pathogens

It may reasonably be thought that the harmful effects of the PV are thus reduced compared to smoking