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Pain 145 , 184195 (2009)

Moreover, in many patients no underlying cause is found, 5 making this condition even more variable

* Based on the trial product estimand: estimated efficacy in an idealized scenario in which all patients stayed on treatment and took no other weight loss therapies

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Oxidative stress sensor Keap1 functions as an adaptor for cul3-based E3 ligase to regulate proteasomal degradation of Nrf2