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Nicotine can also have negative effects on brain development in teenagers

Rigid boxes are typically manufactured using thick chipboard or paperboard wrapped with printed or specialty paper

The high-quality prints are sharp, vivid, and designed to last

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Nicotine may also break down, reducing its potency, while the flavourings can lose their intensity or taste off

Smoking is the leading preventable cause of ill health and early death worldwide, and quitting smoking is vitally important to help people live in good health for longer, says lead author Caitlin Notley, professor of addiction sciences at UEAs Norwich Medical School