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Cigarette smoke contains benzo[a]pyrene, a potent carcinogen that can damage the p53 tumour suppressor gene the gene responsible for preventing abnormal cell growth

The underlying assumption is that even if no one in a particular population of people smoked, there would still be a certain small number of lung cancer deaths, and it is possible to know what that small number would be by, for example, looking at the lung cancer mortality rate among nonsmokers from the CPS-II

It is logical and necessary that tobacco packs and larger health warnings should reflect the many fatal diseases that smoking causes

The results of a regression analysis, which accounted for important confounding factors, were more intuitive and comprehensive than those of a mechanism analysis

It's robust and high in nicotine

This is cheaper than buying cigarettes or even most tobacco products at a convenience store