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For smokers assigned to receive text-only warnings, research staff removed the package cellophane and applied the self-adhesive labels on the side of the packs covering the existing US Surgeon Generals warnings

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Methods: We prospectively re-evaluated COPD exacerbations, spirometric indices, subjective assessments (using the COPD Assessment Tool [CAT] scores), physical activity (measured by the 6-minute walk distance [6MWD]), and conventional cigarette use in EC users with COPD who were retrospectively assessed previously

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