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Warner, PhD The New England Journal of Medicine February 7, 1985 On November 7, 1983

[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Higenbottam T, Shipley MJ, Rose G

The onset of heart trouble in the early 1950s had left her exhausted from full-time work and she had been anxious to stop, but could not say no to Burns

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This may be due to increased mitochondrial ROS levels observed in ARPE-19 cells, which were described to reduce KGDHC activity resulting in -ketoglutarate accumulation [49]