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Exposure to SHS was inversely associated with weight outcome (deficit in weight, risk of underweight, risk of wasting) in 7 of 9 studies 2628,30,31,33,37

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[82] Lateral hypothalamic orexin neurons innervate every component of the ascending reticular activating system (ARAS), which includes noradrenergic, dopaminergic, histaminergic, and serotonergic nuclei that promote wakefulness