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30 In the sirtuin family of proteins, NAD mediates deacetylation, demalonylation/desuccinylation, and ADP-ribosylation of target proteins

Successful treatment of underlying hypogonadism (if present) in conjunction with PT-141 might yield better outcomes, though thats more about identifying other factors rather than measuring PT-141s effect

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Its an Eli Lilly drug, but its been sold as a research molecule since 2023, and thats why so many people, again, in the know in the biohacking space are using it because its literally a profound tool

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Always check storage requirements before traveling with compounded semaglutide