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Although the mechanism by which smoking influences vWF release is not fully understood, it has been suggested that lipid peroxidase formed by O2 free-radicals and the effects of nicotine and CO2 contribute to the increase in vWF functional activity 28

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Moreover, in this study caffeine assumption followed by cigarette smoking was associated with an increase in mitral A a and a reduction in the E a /A a ratio similar to that observed after cigarette smoking alone (Figure 6, top panels)

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As your entire diet