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National Health and Nutrition Examination Survey data found that the normal serum MMA range for the 2.5th to 97.5th percentile of people 70 years, who were considered to be vitamin B12-replete and with normal kidney function, was 84 to 317 nmol/l (Mineva, 2019)

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However, Epithalon remains investigational with no FDA approval, most research conducted in Russia with limited Western replication, long-term human safety data sparse, optimal dosing protocols still debated, and mechanisms not fully understood

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