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The probable reason behind this observation can be the small sample size used for metabolome analysis

Direct-to-consumer subscription models are eroding dependence on the brick-and-mortar channel and reshaping promotional strategies

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Sources HealthLine: Health Sore Throat National Center for Complementay & Integrative Health: Medical Cannabis WebMD: Marijuana Use & Its Effects Leafly: Vaporizing Cannabis Compared to Smoking It

(direct link to download .xlsx file) "Featured Datasets / Tobacco Use Among Adults By Age Group (National Adult Tobacco Survey, NATS)"