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One is familial hypercholesterolemia

NHS guidance supports nicotine replacement therapies for smoking cessation, and pouches function on the same principle

You are more likely to have a painful recovery

On the other hand, the study clearly shows that the incidence of these complications is significantly reduced both in patients who stopped smoking and in those who replaced tobacco cigarettes with e-cigarettes (Figure 4)

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Foulds et al, 2015