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In the intestinal mucosa, MDR1 limits the oral bioavailability of Paclitaxel by promoting its export from epithelial cells (195)

It was where things wound up, sooner or later, and accumulated layer on layer, higher and higher and higher until the entire building would come crashing down under its own weight

4) tolerance, defined as the need for markedly increased amounts of tobacco to achieve the desired effect

Irritant contact stomatitis caused by chemical products used in toothpastes, mouthwashes, and dental restorations can result in oral mucosal injury

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everyone went nuts over it. However, the Brothers faced resistance from Columbia Records president Clive Davis, who wouldnt allow the band to release the song