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These microbial and metabolic alterations highlighted the role of the oral microbiome in tobacco-related diseases, including oral cancer, and suggested its potential for diagnostic and therapeutic applications [81]

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Because nicotine lives at the core of both the problem and the solution to the question of addiction, addressing the addictive levels of nicotine in combustible cigarettes must be part of the FDAs strategy for addressing the devastating, addiction crisis that is threatening American families, said Scott Gottlieb, the FDA commissioner

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April 23, 1988: In 1988, U.S