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However, epidemiological studies assessing Swedish smokeless tobacco, which exposes users to nicotine without combustion products, generally have not found an increased risk of myocardial infarction or stroke among users, but suggest that nicotine might contribute to acute cardiovascular events, especially in those with underlying coronary heart disease
European Heart Journal, 41 (26), 24722483
TRPA1 mediates changes in heart rate variability and cardiac mechanical function in mice exposed to acrolein
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