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The conditioned response is so automatic that quitters frequently report feeling the craving at chai time even months after their last cigarette the conditioned association persists long after the chemical dependency has resolved

Cochrane Database of Systematic Reviews 9, Art

Addictiveness and appeal of ENDS, HTPs and ONPs Nicotine delivery from ENDS, HTPs and ONPs Nicotine is a volatile chemical that is the most abundant tobacco alkaloid and the main addictive component of ENDS, HTPs and ONPs