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The goal is to get nicotine purity up to 99% or higher

The health consequences of smoking: a report of the Surgeon General

A hundred miles northeast of Pittsburgh in the flurrying snow there were numerous roadcuts now, and in them were upward-fining sequences of sandstones, siltstones, shalesAllegheny black shalesunderlying more levels of sandstone, siltstone, and shale

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I was dizzy, nauseous, and I got a headache. [It happened] three weeks ago

(1979 tobacco company Brown and Williamson document) The amount of nicotine a person inhales from a cigarette depends on the smokers puffing behavior