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Taken together, these data suggest that the split-tipping technology in King-sized format might be an effective mechanism for reducing exposure to certain toxicants among smokers, but only for cigarettes with very low ISO tar yield where ventilation levels are greatest

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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

This can significantly influence smoking habits and perceptions

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