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We conducted an a priori power analysis using G*Power Software for independent samples Students t-test 22 , assuming the group difference in mean change of the score is 2 (standard deviation 1.3) 7 and aiming to detect a significance level of 1% and statistical power of 90%, a total sample size of 30 participants (15 in each group) was needed

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There are several different challenges in treating sherm because this kind of addiction has very unpredictable symptoms that can be confused for mental health issues

Most of the current investigations, however, utilized DNA from peripheral lymphocytes or buccal cells only (due to the ease of their sampling) and, thus, did not examine this potential tissue variability

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