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About 440,000 people die each year from smoking-related health problems, and the cost of treatment exceeds $96 billion a year

Vaping has been considered by some as a potentially beneficial harm-reduction tool in the context of tobacco smoking

PINK1-Parkin-mediated mitophagy Serine/threonine PTEN-induced putative kinase 1 (PINK1) is a kinase encoded by the PARK6 gene, and Parkin is an E3 ubiquitin ligase encoded by the PARK2 gene

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E-cigarettes essentially contain nicotine, which is a highly addictive substance found in tobacco cigarettes as well

When exposed to secondhand smoke, children have a decreased risk of ulcerative colitis and an increased risk of developing Crohn's disease